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Home / Blogs / Targeted Therapy vs Immunotherapy: What’s Better?

Targeted Therapy vs Immunotherapy: What’s Better?

20 November 2025

When people come for cancer treatment, this is usually the first question they ask me “Doctor, which is better, targeted therapy or immunotherapy?” And I always say, it depends. These are both strong treatments, but they work in very different ways. What helps one patient may not help another. The right choice depends on your type of cancer, your reports, and how your body reacts.


What Targeted Therapy Means


Targeted therapy is like using a focused tool. It finds and attacks only the cancer cells that have a certain change or weakness. Before starting it, we do some tests on your tumor to check for those changes. If they’re present, this treatment works beautifully. It goes straight to the cancer cell and stops it from growing.
It doesn’t harm the rest of your body the way older drugs did. Most people continue their normal life eating well, working, spending time with family without much trouble. That’s the big advantage of this treatment. The goal is accuracy, not intensity.


What Immunotherapy Does


Immunotherapy is completely different. Instead of fighting the cancer directly, it helps your own body do the fighting. It wakes up your immune system and tells it, “This is what you have to destroy.” In some cancers, this method gives very strong results. Patients who didn’t respond to earlier medicines sometimes respond very well to this one.
The effects are slower, but long-lasting. Some people stay healthy for years with just this treatment. It doesn’t work for every cancer, but when it does, it can change the outcome completely.


How They Differ


The difference is simple. Targeted therapy goes after the cancer cell itself. Immunotherapy strengthens your body to do the job. One acts on the disease, the other through your immunity.
So which one is better? It’s not about better or worse it’s about what suits your case. Your doctor studies the reports and decides what your cancer will respond to best. Sometimes both treatments are combined to get stronger results.


Side Effects and Tolerance


Both treatments are much easier than old chemotherapy. With targeted therapy, you might feel mild tiredness or small skin changes. With immunotherapy, the immune system can get a little too active and cause mild inflammation. But we monitor that closely and control it with medicines.
Most people live a fairly normal routine during treatment. That’s what modern cancer treatment aims for cure without making life harder.


How Doctors Decide


At IOCI, we never guess or generalize. Every patient is different. We check reports, genetic tests, scans, and medical history. Then a senior team reviews which line of therapy targeted therapy or immunotherapy will give the best result.
It’s not just science; it’s judgment. We look at how your body will handle the medicine and what outcome we can realistically expect.


The Bigger Picture


Medicine keeps changing. What was impossible 10 years ago is now normal. Both these treatments have brought new hope to millions of patients. They help people live longer, stronger, and without the pain that older methods often caused. The goal now is not just to fight cancer, but to help you live fully while fighting it.


Why IOCI


At IOCI, we believe in clarity and care. Before starting anything, we explain every detail to you and your family. Our doctors make sure you know what’s being done and why. Every plan is made by an experienced oncology specialist using the latest evidence and safest drugs.
For us, the best treatment is not what’s newest  it’s what’s right for you.

Consult us at any of our locations across IOCI Noida, Greater Noida, Mumbai, Indore, Chh. Sambhajinagar, Agartala, Saharanpur, Kanpur and Jodhpur.